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Month: May 2011

Overall Survival as Endpoint

A commentary published recently in the Journal of Clinical Oncology by Dr. Edward Korn of the NCI, discusses the use of overall survival (OS) as the measure of clinical benefit. This review is divided into three sections, beginning first with situations where identical subsequent therapy is used after both treatment arms and is either differentially […]

Impact of BMI on Response to Endocrine Therapy

Study Design: A retrospective analysis of data from a prospective trial of premenopausal women. The original data came from the Austrian Breast and Colorectal Cancer Study Group 12 (ABCSG-12). This study compared the endocrine treatment of goserelin with tamoxifen versus anastrozole in premenopausal patients with endocrine-responsive breast cancer. Study Eligibility: Premenopausal women with hormone-receptor-positive (estrogen-receptor […]