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Month: May 2012

Supplement on Breast Cancer

The Journal Nature released a supplement on breast cancer today, including two articles on breast cancer metastasis, one on redesigning clinical trials for metastasis, and another on the reality of metastasis, with a discussion of tumor dormancy. MYTHS VS. TRUTHS Brush up on your breast cancer myths and truths. Find out if you know more […]

“Rewiring” Cells to Treat Triple Negative Breast Cancer

Breast cancer cells can be “rewired” to make them more sensitive to chemotherapy, according to a new study published in the journal Cell. Rather than giving targeted therapy and chemotherapy simultaneously, researchers at the Massachusetts Institute of Technology (MIT) pretreated the cancer cells with targeted therapy, making them more susceptible to DNA-damaging chemotherapy. Dr. Michael […]

In mathematical modeling study, investigators find benefits outweigh risks of biennial mammograms for high-risk women in their 40s

A study published in Annals of Internal Medicine using mathematical modeling suggests looking at the level of risk for breast cancer for women in their 40s would aid in determining which women would benefit from mammography screening. In this study, investigators from the NCI’s Cancer Intervention and Surveillance Modeling Network (CISNET) used simulation models to […]

Brachytherapy may increase risk of mastectomy

Brachytherapy is associated with increased risk of subsequent mastectomy and more complications compared to whole-breast irradiation (WBI), according to a new study published in the Journal of the American Medical Association. Moreover, it did not improve survival. In recent years, use of breast brachytherapy, or an implanted radioactive source, after lumpectomy for early breast cancer […]